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Ordering Phoenix Diffusion Cell Cap Kits

Phoenix diffusion cell cap kits are used with the Phoenix DB-6 Manual diffusion system, and the Phoenix RDS (Robotic Diffusion Station) system. Cap kits contain the dosage chamber for the active pharmaceutical ingredient. There are threaded cap kits, press-on cap kits for general applications, and press-on cap kits for skin applications.

Diffusion Cell Cap Kits

In diffusion cell testing, the active pharmaceutical ingredient (API) passes from the dosage chamber into the receptor medium in an amount proportional to the exposed area of the membrane, as determined by the orifice diameter. Phoenix cell cap kits are designed to provide analysts with precise control over this critical factor. In each cell cap kit, the orifices of the dosage chamber above the membrane and the cell cap below the membrane are machined to tight tolerances for diameter and concentricity. Two orifice diameter sizes are available for each small, medium, or large cell. Depending on the cell size and the cap kit selected, orifice diameters range from 9 mm (membrane exposed area 64 mm2) to 20 mm (membrane exposed area 314 mm2). The diameter and height of the dosage chamber above the membrane determines the maximum amount of drug that may be tested. When a greater amount of the formulation is required for a test, select a cap kit with a larger dosage chamber. Two general styles of cap kit are available—threaded and press-on.

Threaded Cap Kit

The threaded style of cap kit includes a threaded clamp ring above the dosage chamber, which allows an adjustable amount of force to be applied to hold the membrane in place. This feature is useful in applications where skin and other membrane types may shrink, swell, or otherwise deform during testing. Threaded cap kits are made from PTFE (polytetrafluoroethylene), sealed with O-rings made from either fluoroelastomer (Viton) or perfluoroelastomer (Kalrez).

Press-On Cap Kit

The press-on style of cap kit is held in place by the friction of the O-ring seals alone. The press-on style is faster to assemble and disassemble. The press-on cap kit for general applications provides a choice of two different dosage chamber heights (4 mm or 20 mm) for each orifice size. The press-on cap kit for skin applications has only one dosage chamber height (7 mm) and one orifice diameter for each cell size. In applications where a smaller membrane is needed, the cap kit for skin applications—when using the small cell size—allows a membrane diameter of 16 mm. Press-on cap kits are made from PEEK (polyether ether ketone), sealed with fluoroelastomer (Viton) O-rings.

Phoenix Threaded Cap Kits

ORDERING INFORMATION – Threaded CAp Kits, Serialized (1 Per Cell)

Also see Ordering Diffusion Cells page and Ordering Mixers page.

For more information, please contact your local Teledyne Hanson representative or email us at:
hansonsales@teledyne.com

 

FOR SMALL CELLS

59-207-210 Threaded Cap Kit, Small, 9 mm, PTFE/Viton

59-207-211 Threaded Cap Kit, Small, 11.3 mm, PTFE/Viton

59-207-212 Threaded Cap Kit, Small, 9 mm, PTFE/Kalrez

59-207-213 Threaded Cap Kit, Small, 11.3 mm, PTFE/Kalrez

FOR MEDIUM CELLS

59-207-225 Threaded Cap Kit, Medium, 11.3 mm, PTFE/Viton

59-207-226 Threaded Cap Kit, Medium, 15 mm, PTFE/Viton

59-207-227 Threaded Cap Kit, Medium, 11.3 mm, PTFE/Kalrez

59-207-228 Threaded Cap Kit, Medium, 15 mm, PTFE/Kalrez

FOR LARGE CELLS

59-207-240 Threaded Cap Kit, Large, 15 mm, PTFE/Viton

59-207-241 Threaded Cap Kit, Large, 20 mm, PTFE/Viton

59-207-242 Threaded Cap Kit, Large, 15 mm, PTFE/Kalrez

59-207-243 Threaded Cap Kit, Large, 20 mm, PTFE/Kalrez

Phoenix Press-On Cap Kits – General Applications

ORDERING INFORMATION – Press-On CAp Kits, Serialized (1 Per Cell)

Also see Ordering Diffusion Cells page and Ordering Mixers page.

For more information, please contact your local Teledyne Hanson representative or email us at:
hansonsales@teledyne.com

 

FOR SMALL CELLS

59-207-201 Press-on Cap Kit, Small, 9 mm X 4 mm, PEEK

59-207-202 Press-on Cap Kit, Small, 9 mm X 20 mm, PEEK

59-207-203 Press-on Cap Kit, Small, 11.3 mm X 4 mm, PEEK

59-207-204 Press-on Cap Kit, Small, 11.3 mm X 20 mm, PEEK

FOR MEDIUM CELLS

59-207-215 Press-on Cap Kit, Medium, 11.3 mm X 4 mm, PEEK

59-207-216 Press-on Cap Kit, Medium, 11.3 mm X 20 mm, PEEK

59-207-217 Press-on Cap Kit, Medium, 15 mm X 4 mm, PEEK

59-207-218 Press-on Cap Kit, Medium, 15 mm X 20 mm, PEEK

FOR LARGE CELLS

59-207-231 Press-on Cap Kit, Large, 15 mm X 4 mm, PEEK

59-207-232 Press-on Cap Kit, Large, 15 mm X 20 mm, PEEK

59-207-233 Press-on Cap Kit, Large, 20 mm X 4 mm, PEEK

59-207-234 Press-on Cap Kit, Large, 20 mm X 20 mm, PEEK

Phoenix Press-On Cap Kits – Skin Applications

ORDERING INFORMATION – Press-On CAp Kits, Skin, Serialized (1 Per Cell)

Also see Ordering Diffusion Cells page and Ordering Mixers page.

For more information, please contact your local Teledyne Hanson representative or email us at:
hansonsales@teledyne.com

 

FOR SMALL CELLS

59-207-205 Press-on Cap Kit, Skin, Small, 11.3 mm, PEEK

FOR MEDIUM CELLS

59-207-221 Press-on Cap Kit, Skin, Medium, 15 mm, PEEK

FOR LARGE CELLS

59-207-235 Press-on Cap Kit, Skin, Large, 20 mm, PEEK

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