Dissolution testing determines the release rate of an active pharmaceutical ingredient in tablet or capsule form as it dissolves into solution. Dissolution replicates the process of oral dosage formulations as they dissolve and are assimilated into the GI tract.
The Vision G2 Classic 6 dissolution tester is a compact, rugged workhorse, precision engineered to ease the rigors of manual dissolution testing. The Vision G2 Elite 8 dissolution tester is a versatile performance machine, built with the highest quality components and engineering for automated dissolution testing.
The CD14 Comparative Dissolution with 14 vessels allows testing of two different drugs at once. Teledyne Hanson’s Super Precision Vessel™ with its closer conformance to an ideal vessel shape provides more consistent vessel-to-vessel dissolution test results in USP Apparatus 2.
Vision AutoPlus™ and CD AutoPlus™ Autosamplers
Vision AutoPlus autosamplers are designed for seamless integration with Vision G2 Classic 6™ and Vision G2 Elite 8™ dissolution testers. The Vision AutoPlus offers precision pump mechanics, all-inert syringes, valves, tubing, and fluidics, and a choice of 6 or 8 sampling channels in DissoScan™ (single-bath) or Maximizer™ (multi-bath) configurations. The new CD AutoPlus, with equally precise mechanics and inert components, is designed for plug-and-play operation with 14-vessel CD14 Comparative Dissolution Testers. With 10 mL syringes and a volume accuracy of ± 1%, the CD AutoPlus easily accommodates sampling intervals under 5 minutes.
Dissolution labs running Hanson Vision G2 instruments can now manage protocols and instruments more efficiently than ever before. Hanson’s new Protocol Manager eliminates all connectivity and storage limits by connecting your Vision G2 systems to a centralized protocol database and a spacious, easy to use interface, with unlimited capacity, drag-and-drop simplicity, and increased support for 21 CFR Part 11 compliance.
Automatic Media Preparation
The Media-Mate Plus is the perfect media-prep system for a busy dissolution lab that demands both speed and accuracy. It delivers pre-heated, filtered, deaerated, and volumetrically dispensed media to 6 or 7 dissolution vessels simultaneously in less than five minutes.
The UV-1900 series provides a compact, double-beam UV-Vis spectrophotometer wrapped in a sleek form. The UV-1900 series, made by Shimadzu for Teledyne Hanson, uses the Czerny-Turner mounting for its monochromator, and boasts the highest resolution in its class, a bright optical system, and a compact design.
Teledyne Hanson offers a large range of accessories to accommodate numerous dissolution applications. These applications include small volume testing, Chinese small volume testing, and an immersion cell application which is done in a small volume vessel. Other applications include a stationary basket and cover, a fiber optic cover, USP Apparatus 5 – paddle over disk (transdermal sandwich), and USP Apparatus 6 – rotating cylinder. For details on all available applications see Dissolution Applications.