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Dissolution Testing

Baskets and Paddles

Choose from a variety of baskets (USP Apparatus 1), and paddles (USP Apparatus 2) for one liter and two liter dissolution testing, as well as mini baskets and mini paddles for small volume (150 mL), Chinese small volume (250 mL), and immersion cell applications. The Teledyne Hanson spin-shaft design allows quick changeover of the lower apparatus portion from the upper shaft, which remains firmly in place to maintain accurate height measurements, especially when switching between different apparatus types. The baskets and paddles described below are used with your Vision G2 Elite 8, Vision G2 Classic 6, or CD14 dissolution testers.
 

USP APPARATUS 2 – Paddles

Spin-paddles (USP Apparatus 2) are available in 1-liter 316 stainless steel (74-105-202) or PVDF (74-105-201), or 2-liter 316 stainless steel  (74-105-361) or PVDF (74-105-351). All spin paddles are serialized. The spin-paddles can be used for testing transdermal products within the dissolution tester, such as paddle-over-disk (USP Apparatus 5). They are designed for use with Vision G2 Classic 6, Vision G2 Elite 8 (1 and 2-liter), and CD14 dissolution testers.

 

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USP APPARATUS 1 – Baskets

USP Apparatus 1 baskets for use in Teledyne Hanson testers are made of 316 stainless steel including the 40-mesh basket (74-105-252), the 10-mesh (65-220-010), and the 20-mesh (65-220-020). Each basket has a unique serial number. Basket are attached to serialized spin shafts made of 316 stainless steel. Spin shafts are available for 1-liter vessels (74-105-251) and 2-liter vessels (74-105-371). All baskets are compatible with the six-vessel Vision G2 Classic 6, the eight-vessel Vision G2 Elite 8, and our 14-vessel CD14 dissolution testers.

 

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Mini Baskets and Mini Paddles

The mini basket (74-105-220) for small volume dissolution is made of 40-mesh type 316 stainless steel and is serialized. The mini spin-shaft (74-105-220) required for this application is also made from 316 stainless steel and is serialized. The serialized mini spin-paddles for small volume (150 mL) dissolution, are available PTFE-coated (74-105-203) or made of  316 stainless steel (74-105-204). These mini paddles are also used in immersion cell applications per USP <1724>. For Chinese small volume (250 mL CSV) applications a 316 stainless steel mini spin-paddle (74-105-290) is available.

 

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STATIONARY Baskets

An 8-mesh stationary basket (95-590-150) made of 316 stainless steel helps with problems associated with floating, sticking, and swelling dosage forms, and complies with the USP Monograph for Felodipine Extended-Release tablets. The stationary basket cover (74-107-019) accommodates the 1-liter vessel and the stationary basket.

 

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USP APPARATUS 1 – Suppository Baskets

Teledyne Hanson offers a USP Apparatus 1 basket specifically designed for suppositories (65-700-048). Attach it to a USP 316 stainless steel basket shaft (74-105-251) for suppository testing. The basket  is compatible with the six-vessel Vision G2 Classic 6, the eight-vessel Vision G2 Elite 8, and our 14-vessel CD14 dissolution testers.

 

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